8FW8
MtrR from Neisseria gonorrhoeae bound to Progesterone
Summary for 8FW8
| Entry DOI | 10.2210/pdb8fw8/pdb |
| Descriptor | HTH-type transcriptional regulator MtrR, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION, ... (5 entities in total) |
| Functional Keywords | hth, regulator, hormone, induction, transcription |
| Biological source | Neisseria gonorrhoeae |
| Total number of polymer chains | 4 |
| Total formula weight | 99647.52 |
| Authors | Hooks, G.H.,Brennan, R.G. (deposition date: 2023-01-20, release date: 2024-01-24, Last modification date: 2024-04-03) |
| Primary citation | Hooks, G.M.,Ayala, J.C.,Holley, C.L.,Dhulipala, V.,Beggs, G.A.,Perfect, J.R.,Schumacher, M.A.,Shafer, W.M.,Brennan, R.G. Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR. Nat Commun, 15:1153-1153, 2024 Cited by PubMed: 38326294DOI: 10.1038/s41467-024-45195-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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