8FVT
Multi-state design of two-state switchable hinge proteins
Summary for 8FVT
Entry DOI | 10.2210/pdb8fvt/pdb |
Descriptor | 3hb12 (1 entity in total) |
Functional Keywords | de novo protein, metamorphic proteins, switchable hinge proteins, protein dynamics, three-helix bundles |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 22386.66 |
Authors | Bera, A.K.,Broerman, A.,Baker, D. (deposition date: 2023-01-19, release date: 2023-08-16, Last modification date: 2024-03-06) |
Primary citation | Praetorius, F.,Leung, P.J.Y.,Tessmer, M.H.,Broerman, A.,Demakis, C.,Dishman, A.F.,Pillai, A.,Idris, A.,Juergens, D.,Dauparas, J.,Li, X.,Levine, P.M.,Lamb, M.,Ballard, R.K.,Gerben, S.R.,Nguyen, H.,Kang, A.,Sankaran, B.,Bera, A.K.,Volkman, B.F.,Nivala, J.,Stoll, S.,Baker, D. Design of stimulus-responsive two-state hinge proteins. Science, 381:754-760, 2023 Cited by PubMed: 37590357DOI: 10.1126/science.adg7731 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.07 Å) |
Structure validation
Download full validation report