8FRZ

Full-length mouse 5-HT3A receptor in complex with serotonin, pre-activated

Summary for 8FRZ

• Entry DOI: 10.2210/pdb8frz/pdb
• EMDB information: 29409 29410 29411 29418
• Descriptor: 5-hydroxytryptamine receptor 3A, SEROTONIN, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: partial agonist, cys-loop, plgic, ion channel, transport protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 5
• Total formula weight: 315948.26

Authors

Felt, K.C.,Chakrapani, S. (deposition date: 2023-01-09, release date: 2023-12-27, Last modification date: 2024-05-01)

• Primary citation: Felt, K.,Stauffer, M.,Salas-Estrada, L.,Guzzo, P.R.,Xie, D.,Huang, J.,Filizola, M.,Chakrapani, S.; Structural basis for partial agonism in 5-HT 3A receptors.; Nat.Struct.Mol.Biol., 31:598-609, 2024; PubMed: 38177669; DOI: 10.1038/s41594-023-01140-2

Experimental method

ELECTRON MICROSCOPY (2.75 Å)