8FR2

Carbonic Anhydrase IX-mimic in complex with the alkyl urea compound 3h

Summary for 8FR2

Entry DOI	10.2210/pdb8fr2/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, ... (5 entities in total)
Functional Keywords	inhibitor, metal binding protein, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29430.43
Authors	Combs, J.C.,McKenna, R. (deposition date: 2023-01-06, release date: 2023-02-01, Last modification date: 2024-05-22)
Primary citation	Combs, J.,Bozdag, M.,Cravey, L.D.,Kota, A.,McKenna, R.,Angeli, A.,Carta, F.,Supuran, C.T. New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28:-, 2023 Cited by PubMed: 36677947 DOI: 10.3390/molecules28020890 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.307 Å)

Structure validation