8FQX

Carbonic Anhydrase II in complex with the alkyl ureas 3g

Summary for 8FQX

Entry DOI	10.2210/pdb8fqx/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, ... (6 entities in total)
Functional Keywords	inhibitor, metal binding protein, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29847.04
Authors	Combs, J.E.,McKenna, R. (deposition date: 2023-01-06, release date: 2023-02-01, Last modification date: 2024-05-22)
Primary citation	Combs, J.,Bozdag, M.,Cravey, L.D.,Kota, A.,McKenna, R.,Angeli, A.,Carta, F.,Supuran, C.T. New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules, 28:-, 2023 Cited by PubMed: 36677947 DOI: 10.3390/molecules28020890 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.496 Å)

Structure validation