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8FJ7

LSD1-CoREST in complex with T108 and SNAG peptide

Summary for 8FJ7
Entry DOI10.2210/pdb8fj7/pdb
DescriptorLysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ... (4 entities in total)
Functional Keywordsepigenetics, histone demethylase, drug resistance, covalent inhibitor, oxidoreductase
Biological sourceHomo sapiens (human)
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Total number of polymer chains3
Total formula weight113652.57
Authors
Caroli, J.,Mattevi, A. (deposition date: 2022-12-19, release date: 2024-06-26)
Primary citationCaroli, J.,Mattevi, A.
Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published,
Experimental method
Structure validation

223790

数据于2024-08-14公开中

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