8FJ7
LSD1-CoREST in complex with T108 and SNAG peptide
Summary for 8FJ7
Entry DOI | 10.2210/pdb8fj7/pdb |
Descriptor | Lysine-specific histone demethylase 1A, REST corepressor 1, Zinc finger protein SNAI1, ... (4 entities in total) |
Functional Keywords | epigenetics, histone demethylase, drug resistance, covalent inhibitor, oxidoreductase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 113652.57 |
Authors | |
Primary citation | Caroli, J.,Mattevi, A. Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published, |
Experimental method |
Structure validation
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