8FH5

Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001

8FH5 の概要

• エントリーDOI: 10.2210/pdb8fh5/pdb
• 分子名称: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl)acetic acid, ... (4 entities in total)
• 機能のキーワード: complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36931.90

構造登録者

Arenas, R.,Wilson, D.K. (登録日: 2022-12-13, 公開日: 2023-12-20)

• 主引用文献: Arenas, R.,Wilson, D.K.; Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001; To Be Published,

実験手法

X-RAY DIFFRACTION (1.62 Å)