8FFX

Crystal structure of HIV-1 reverse transcriptase in complex with non-nucleoside inhibitor 19980

8FFX の概要

• エントリーDOI: 10.2210/pdb8ffx/pdb
• 分子名称: Reverse transcriptase/ribonuclease H, p51 RT, DIMETHYL SULFOXIDE, ... (7 entities in total)
• 機能のキーワード: non nucleotide-reverse transcriptase inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 BH10; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114835.54

構造登録者

Rumrill, S.R.,Ruiz, F.X.,Arnold, E. (登録日: 2022-12-10, 公開日: 2023-04-26, 最終更新日: 2024-05-22)

• 主引用文献: Mansouri, M.,Rumrill, S.,Dawson, S.,Johnson, A.,Pinson, J.A.,Gunzburg, M.J.,Latham, C.F.,Barlow, N.,Mbogo, G.W.,Ellenberg, P.,Headey, S.J.,Sluis-Cremer, N.,Tyssen, D.,Bauman, J.D.,Ruiz, F.X.,Arnold, E.,Chalmers, D.K.,Tachedjian, G.; Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach.; Molecules, 28:-, 2023; PubMed: 37049868; DOI: 10.3390/molecules28073103

実験手法

X-RAY DIFFRACTION (2.42 Å)