8FFQ

Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red

Summary for 8FFQ

Entry DOI	10.2210/pdb8ffq/pdb
EMDB information	29051
Descriptor	Transient receptor potential cation channel subfamily V member 5, ERGOSTEROL, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2), ... (4 entities in total)
Functional Keywords	trpv5, trp channel, ruthenium red, pi(4, 5)p2, membrane protein
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	4
Total formula weight	341903.29
Authors	De Jesus-Perez, J.J.,Fluck, E.C.,Pumroy, R.A.,Protopopova, A.D.,Rocereta, J.A.,Moiseenkova-Bell, V.Y. (deposition date: 2022-12-09, release date: 2024-02-07, Last modification date: 2024-02-21)
Primary citation	Pumroy, R.A.,De Jesus-Perez, J.J.,Protopopova, A.D.,Rocereta, J.A.,Fluck, E.C.,Fricke, T.,Lee, B.H.,Rohacs, T.,Leffler, A.,Moiseenkova-Bell, V. Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25:506-523, 2024 Cited by PubMed: 38225355 DOI: 10.1038/s44319-023-00050-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.65 Å)

Structure validation