8FFF
Crystal structure of Staphylococcus aureus D-alanine D-alanine ligase enzyme in complex with acetate
Summary for 8FFF
Entry DOI | 10.2210/pdb8fff/pdb |
Descriptor | D-alanine--D-alanine ligase, ACETATE ION (3 entities in total) |
Functional Keywords | d-alanine d-alanie, s.aureus, cell wall biosynthesis, omega loop, ligase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 40161.23 |
Authors | Jayasinghe, Y.P.,Ronning, D.R. (deposition date: 2022-12-08, release date: 2024-05-08, Last modification date: 2024-05-15) |
Primary citation | Panda, S.,Jayasinghe, Y.P.,Shinde, D.D.,Bueno, E.,Stastny, A.,Bertrand, B.P.,Chaudhari, S.S.,Kielian, T.,Cava, F.,Ronning, D.R.,Thomas, V.C. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity. Biorxiv, 2024 Cited by PubMed: 38293037DOI: 10.1101/2024.01.15.575639 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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