8FDB

CRYSTAL STRUCTURE OF NAGB-II PHOSPHOSUGAR ISOMERASE FROM Shewanella denitrificans OS217 IN COMPLEX WITH GLUCITOLAMINE-6-PHOSPHATE AT 3.06 A RESOLUTION.

Summary for 8FDB

Entry DOI	10.2210/pdb8fdb/pdb
Descriptor	Glutamine-fructose-6-phosphate transaminase (Isomerizing), 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	deaminase isomerization-deamination amino-sugar metabolism positive cooperativity and allosteric activation sugar-isomerase domain, isomerase
Biological source	Shewanella denitrificans OS217 More
Total number of polymer chains	2
Total formula weight	72274.39
Authors	Rodriguez-Romero, A.,Rodriguez-Hernandez, A.,Marcos-Viquez, J.,Bustos-Jaimes, I. (deposition date: 2022-12-02, release date: 2023-05-17, Last modification date: 2023-06-07)
Primary citation	Marcos-Viquez, J.,Rodriguez-Hernandez, A.,Alvarez-Anorve, L.I.,Medina-Garcia, A.,Plumbridge, J.,Calcagno, M.L.,Rodriguez-Romero, A.,Bustos-Jaimes, I. Substrate binding in the allosteric site mimics homotropic cooperativity in the SIS-fold glucosamine-6-phosphate deaminases. Protein Sci., 32:e4651-e4651, 2023 Cited by PubMed: 37145875 DOI: 10.1002/pro.4651 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.06 Å)

Structure validation