8FAO

Bile Salt Hydrolase B from Lactobacillus gasseri with covalent inhibitor bound

Summary for 8FAO

• Entry DOI: 10.2210/pdb8fao/pdb
• Descriptor: Choloylglycine hydrolase, (5R)-5-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-1-fluorohexan-2-one (non-preferred name), NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: bile salt hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Lactobacillus gasseri
• Total number of polymer chains: 8
• Total formula weight: 300447.27

Authors

Grundy, M.K.,Walker, M.E.,Redinbo, M.R. (deposition date: 2022-11-28, release date: 2023-12-13)

• Primary citation: Grundy, M.K.,Walker, M.E.,Redinbo, M.R.; Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.14 Å)