8F80

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM738

8F80 の概要

• エントリーDOI: 10.2210/pdb8f80/pdb
• 分子名称: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-[2-(3-{[2,4-diamino-6-(4-methoxyphenyl)pyrimidin-5-yl]oxy}propoxy)phenyl]propanoic acid, ... (6 entities in total)
• 機能のキーワード: ssgcid, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Mycobacterium ulcerans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20371.66

構造登録者

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2022-11-21, 公開日: 2023-12-13)

• 主引用文献: Liu, L.,Battaile, K.P.,Lovell, S.,Staker, B.L.; Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM738; To be published,

実験手法

X-RAY DIFFRACTION (1.1 Å)