8F6R

CryoEM structure of designed modular protein oligomer C6-79

Summary for 8F6R

• Entry DOI: 10.2210/pdb8f6r/pdb
• EMDB information: 28889
• Descriptor: De novo designed oligomeric protein C6-79 (1 entity in total)
• Functional Keywords: synthetic, self-assembling, oligomeric, helical repeats, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 6
• Total formula weight: 161305.21

Authors

Redler, R.L.,Edman, N.I.,Baker, D.,Ekiert, D.,Bhabha, G. (deposition date: 2022-11-17, release date: 2023-11-29, Last modification date: 2024-07-24)

• Primary citation: Edman, N.I.,Phal, A.,Redler, R.L.,Schlichthaerle, T.,Srivatsan, S.R.,Ehnes, D.D.,Etemadi, A.,An, S.J.,Favor, A.,Li, Z.,Praetorius, F.,Gordon, M.,Vincent, T.,Marchiano, S.,Blakely, L.,Lin, C.,Yang, W.,Coventry, B.,Hicks, D.R.,Cao, L.,Bethel, N.,Heine, P.,Murray, A.,Gerben, S.,Carter, L.,Miranda, M.,Negahdari, B.,Lee, S.,Trapnell, C.,Zheng, Y.,Murry, C.E.,Schweppe, D.K.,Freedman, B.S.,Stewart, L.,Ekiert, D.C.,Schlessinger, J.,Shendure, J.,Bhabha, G.,Ruohola-Baker, H.,Baker, D.; Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.; Cell, 187:3726-3740.e43, 2024; PubMed: 38861993; DOI: 10.1016/j.cell.2024.05.025

Experimental method