8F3N

Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion penicillin bound form from Enterococcus faecium

Summary for 8F3N

• Entry DOI: 10.2210/pdb8f3n/pdb
• Related: 8F3F
• Descriptor: Penicillin binding protein 5, OPEN FORM - PENICILLIN G, SULFATE ION, ... (4 entities in total)
• Functional Keywords: penicillin binding, antibiotic resistance, antibiotics, antibiotic
• Biological source: Enterococcus faecium
• Total number of polymer chains: 1
• Total formula weight: 72334.68

Authors

D'Andrea, E.D.,Choy, M.S.,Schoenle, M.V.,Page, R.,Peti, W. (deposition date: 2022-11-10, release date: 2023-07-05, Last modification date: 2024-10-30)

• Primary citation: Hunashal, Y.,Kumar, G.S.,Choy, M.S.,Da Silva Santiago, A.,D'Andrea, E.D.,Schoenle, M.V.,Arthur, M.,Rice, L.B.,Page, R.,Peti, W.; The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics; Nat Commun, 2023

Experimental method

X-RAY DIFFRACTION (2.99 Å)