8F1X
EGFR kinase in complex with mobocertinib (TAK-788)
Summary for 8F1X
Entry DOI | 10.2210/pdb8f1x/pdb |
Descriptor | Epidermal growth factor receptor, propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate (3 entities in total) |
Functional Keywords | egfr, kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 38224.15 |
Authors | |
Primary citation | Beyett, T.S.,Eck, M.J. EGFR kinase in complex with mobocertinib (TAK-788) To be published, |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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