8F1X

EGFR kinase in complex with mobocertinib (TAK-788)

8F1X の概要

• エントリーDOI: 10.2210/pdb8f1x/pdb
• 分子名称: Epidermal growth factor receptor, propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate (3 entities in total)
• 機能のキーワード: egfr, kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38224.15

構造登録者

Beyett, T.S.,Eck, M.J. (登録日: 2022-11-06, 公開日: 2023-11-08)

• 主引用文献: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with mobocertinib (TAK-788); To be published,

実験手法

X-RAY DIFFRACTION (2.3 Å)