8F1S

A benzimidazole (DB1476) sequence-specific recognition of 5'-CGCAAAAAAGCG-3' in A-orientation

Summary for 8F1S

• Entry DOI: 10.2210/pdb8f1s/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*TP*GP*CP*G)-3'), 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), ... (5 entities in total)
• Functional Keywords: dna, minor groove binder, minor groove, sequence recognition
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 7703.52

Authors

Ogbonna, E.N.,Wilson, W.D. (deposition date: 2022-11-06, release date: 2023-02-22, Last modification date: 2023-10-25)

• Primary citation: Ogbonna, E.N.,Paul, A.,Farahat, A.A.,Terrell, J.R.,Mineva, E.,Ogbonna, V.,Boykin, D.W.,Wilson, W.D.; X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.; Acs Bio Med Chem Au, 3:335-348, 2023; PubMed: 37599788; DOI: 10.1021/acsbiomedchemau.3c00002

Experimental method

X-RAY DIFFRACTION (2.1 Å)