8F0N

Wobble Beetroot (A16U-U38G) dimer bound to DFHO

Summary for 8F0N

Entry DOI	10.2210/pdb8f0n/pdb
Descriptor	RNA (49-MER), POTASSIUM ION, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total)
Functional Keywords	rna, aptamer, fluorescence, turn-on, fluorogenic, fluorophore, g-quartet, g-quadruplex
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	32836.94
Authors	Passalacqua, L.F.M.,Ferre-D'Amare, A.R. (deposition date: 2022-11-03, release date: 2023-05-31, Last modification date: 2023-10-25)
Primary citation	Passalacqua, L.F.M.,Starich, M.R.,Link, K.A.,Wu, J.,Knutson, J.R.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R. Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14:2969-2969, 2023 Cited by PubMed: 37221204 DOI: 10.1038/s41467-023-38683-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation