8F0L
Crystal Structure of the Human T cell Receptor CD3(EPSILON) N-Terminal Peptide Complexed with ADI-26906 FAB
Summary for 8F0L
Entry DOI | 10.2210/pdb8f0l/pdb |
Descriptor | ADI-26906 Fab Heavy Chain, ADI-26906 Fab Light Chain, T-cell surface glycoprotein CD3 epsilon chain, ... (5 entities in total) |
Functional Keywords | cd3 epsilon, antibody-antigen complex, membrane protein-immune system complex, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 99683.03 |
Authors | Battles, M.B.,Welin, M. (deposition date: 2022-11-03, release date: 2023-03-29, Last modification date: 2024-10-16) |
Primary citation | Liu, C.Y.,Ahonen, C.L.,Brown, M.E.,Zhou, L.,Welin, M.,Krauland, E.M.,Pejchal, R.,Widboom, P.F.,Battles, M.B. Structure-based engineering of a novel CD3 epsilon-targeting antibody for reduced polyreactivity. Mabs, 15:2189974-2189974, 2023 Cited by PubMed: 36991534DOI: 10.1080/19420862.2023.2189974 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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