8EYV

Structure of Beetroot dimer bound to DFHO

8EYV の概要

• エントリーDOI: 10.2210/pdb8eyv/pdb
• 分子名称: RNA (45-MER), POTASSIUM ION, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total)
• 機能のキーワード: rna, aptamer, fluorescence, turn-on, fluorogenic, fluorophore, g-quartet, g-quadruplex
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32804.94

構造登録者

Passalacqua, L.F.M.,Ferre-D'Amare, A.R. (登録日: 2022-10-28, 公開日: 2023-05-31, 最終更新日: 2023-10-25)

• 主引用文献: Passalacqua, L.F.M.,Starich, M.R.,Link, K.A.,Wu, J.,Knutson, J.R.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R.; Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.; Nat Commun, 14:2969-2969, 2023; PubMed: 37221204; DOI: 10.1038/s41467-023-38683-3

実験手法

X-RAY DIFFRACTION (2.55 Å)