8EWA

Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13644923

8EWA の概要

• エントリーDOI: 10.2210/pdb8ewa/pdb
• 分子名称: UDP-N-acetylmuramate--L-alanine ligase, (2R)-2-({4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)-2-phenylethyl (2R)-2-(aminomethyl)morpholine-4-carboxylate, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: ssgcid, murc, cell wall biogenesis, peptidoglycan biosynthesis, structural genomics, seattle structural genomics center for infectious disease, ligase
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69278.15

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2022-10-21, 公開日: 2022-11-09, 最終更新日: 2023-10-18)

• 主引用文献: Abendroth, J.,Hill, P.,Horanyi, P.S.,Lorimer, D.D.,Edwards, T.E.; Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13644923; to be published,

実験手法

X-RAY DIFFRACTION (1.85 Å)