8EV5
NlpC B3 covalently bound with E64 inhibitor fragment
Summary for 8EV5
Entry DOI | 10.2210/pdb8ev5/pdb |
Descriptor | Clan CA, family C40, NlpC/P60 superfamily cysteine peptidase, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nlpc, p60, chap, nlpc/p60, cysteine protease, inhibitor, e64, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Trichomonas vaginalis |
Total number of polymer chains | 1 |
Total formula weight | 13670.52 |
Authors | |
Primary citation | Barnett, M.J.,Pinheiro, J.,Keown, J.R.,Biboy, J.,Gray, J.,Lucinescu, I.W.,Vollmer, W.,Hirt, R.P.,Simoes-Barbosa, A.,Goldstone, D.C. NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli. Plos Pathog., 19:e1011563-e1011563, 2023 Cited by PubMed: 37585473DOI: 10.1371/journal.ppat.1011563 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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