8ESK
Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with rocuronium, resting-like state
Summary for 8ESK
Entry DOI | 10.2210/pdb8esk/pdb |
EMDB information | 28576 |
Descriptor | Acetylcholine receptor subunit alpha, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, ... (12 entities in total) |
Functional Keywords | acetylcholine receptor, nicotinic receptor, torpedo, cys-loop receptor, ion channel, muscle-type nicotinic receptor, transport protein-inhibitor complex, neuromuscular blocker, inhibitor, transport protein/inhibitor |
Biological source | Tetronarce californica (Pacific electric ray) More |
Total number of polymer chains | 5 |
Total formula weight | 281385.21 |
Authors | Goswami, U.,Rahman, M.M.,Teng, J.,Hibbs, R.E. (deposition date: 2022-10-14, release date: 2023-06-07, Last modification date: 2023-06-14) |
Primary citation | Goswami, U.,Rahman, M.M.,Teng, J.,Hibbs, R.E. Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. Nat Commun, 14:3169-3169, 2023 Cited by PubMed: 37264005DOI: 10.1038/s41467-023-38827-5 PDB entries with the same primary citation |
Experimental method |
Structure validation
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