8ERT

NLRP3 PYD filament

Summary for 8ERT

• Entry DOI: 10.2210/pdb8ert/pdb
• EMDB information: 28560
• Descriptor: NACHT, LRR and PYD domains-containing protein 3 (1 entity in total)
• Functional Keywords: inflammasome, cytosolic protein, cytosolic protein-transferase complex, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 21
• Total formula weight: 234085.74

Authors

Wu, H.,Xiao, L. (deposition date: 2022-10-12, release date: 2022-12-14, Last modification date: 2024-06-19)

• Primary citation: Xiao, L.,Magupalli, V.G.,Wu, H.; Cryo-EM structures of the active NLRP3 inflammasome disc.; Nature, 613:595-600, 2023; PubMed: 36442502; DOI: 10.1038/s41586-022-05570-8

Experimental method

ELECTRON MICROSCOPY (3.3 Å)