8EOY

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI37

Summary for 8EOY

• Entry DOI: 10.2210/pdb8eoy/pdb
• Descriptor: 3C-like proteinase, benzyl {(2S)-1-[2-(3-amino-3-oxopropyl)-2-(chloroacetyl)hydrazinyl]-4-methyl-1-oxopentan-2-yl}carbamate (non-preferred name) (3 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus)
• Total number of polymer chains: 2
• Total formula weight: 68568.88

Authors

Yang, K.S.,Liu, W.R. (deposition date: 2022-10-04, release date: 2023-10-11, Last modification date: 2024-10-23)

• Primary citation: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.28 Å)