8EOY

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI37

8EOY の概要

• エントリーDOI: 10.2210/pdb8eoy/pdb
• 分子名称: 3C-like proteinase, benzyl {(2S)-1-[2-(3-amino-3-oxopropyl)-2-(chloroacetyl)hydrazinyl]-4-methyl-1-oxopentan-2-yl}carbamate (non-preferred name) (3 entities in total)
• 機能のキーワード: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68568.88

構造登録者

Yang, K.S.,Liu, W.R. (登録日: 2022-10-04, 公開日: 2023-10-11, 最終更新日: 2023-11-15)

• 主引用文献: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.28 Å)