8EKE
Cryo-EM structure of SARS CoV-2 Mpro WT protease
Summary for 8EKE
| Entry DOI | 10.2210/pdb8eke/pdb |
| EMDB information | 28200 |
| Descriptor | 3C-like proteinase nsp5 (1 entity in total) |
| Functional Keywords | main protease, mpro, sars cov-2, polyprotein, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, 2019-nCoV, COVID-19 virus) |
| Total number of polymer chains | 2 |
| Total formula weight | 67586.96 |
| Authors | Narwal, M.,Edwards, T.,Armache, J.P.,Murakami, K.S. (deposition date: 2022-09-20, release date: 2023-04-26, Last modification date: 2024-06-19) |
| Primary citation | Narwal, M.,Armache, J.P.,Edwards, T.J.,Murakami, K.S. SARS-CoV-2 polyprotein substrate regulates the stepwise M pro cleavage reaction. J.Biol.Chem., 299:104697-104697, 2023 Cited by PubMed: 37044215DOI: 10.1016/j.jbc.2023.104697 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.36 Å) |
Structure validation
Download full validation report
