8EDP
Crystal structure of a three-tetrad, parallel, and K+ stabilized homopurine G-quadruplex from human chromosome 7
Summary for 8EDP
Entry DOI | 10.2210/pdb8edp/pdb |
Descriptor | DNA (5'-D(*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*G)-3'), COBALT HEXAMMINE(III), POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | g-quadruplex, parallel, propeller loops, three-tetrad, dna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 8907.43 |
Authors | Ye, M.,Yatsunyk, L.A. (deposition date: 2022-09-05, release date: 2022-12-28, Last modification date: 2024-05-22) |
Primary citation | Ye, M.,Chen, E.V.,Pfeil, S.H.,Martin, K.N.,Atrafi, T.,Yun, S.,Martinez, Z.,Yatsunyk, L.A. Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77:117112-117112, 2022 Cited by PubMed: 36508994DOI: 10.1016/j.bmc.2022.117112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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