8EAC
Thermus thermophilus methylenetetrahydrofolate reductase
Summary for 8EAC
| Entry DOI | 10.2210/pdb8eac/pdb |
| Descriptor | Methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
| Functional Keywords | tim barrel, flavin, oxidoreductase |
| Biological source | Thermus thermophilus HB8 |
| Total number of polymer chains | 2 |
| Total formula weight | 66887.32 |
| Authors | Yamada, K.,Koutmos, M. (deposition date: 2022-08-28, release date: 2023-01-18, Last modification date: 2023-10-25) |
| Primary citation | Yamada, K.,Mendoza, J.,Koutmos, M. 5-Formyltetrahydrofolate promotes conformational remodeling in a methylenetetrahydrofolate reductase active site and inhibits its activity. J.Biol.Chem., 299:102855-102855, 2022 Cited by PubMed: 36592927DOI: 10.1016/j.jbc.2022.102855 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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