8E77

rystal structure of Pcryo_0616, the aminotransferase required to synthesize UDP-N-acetyl-3-amino-D-glucosaminuronic acid (UDP-GlcNAc3NA), incomplete with its external aldimine reaction intermediate

8E77 の概要

• エントリーDOI: 10.2210/pdb8e77/pdb
• 関連するPDBエントリー: 8e75
• 分子名称: DegT/DnrJ/EryC1/StrS aminotransferase, (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name), 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: aminotransferase, psychrobacter cryohalolentis, carbohydrate, transferase
• 由来する生物種: Psychrobacter cryohalolentis K5
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43281.34

構造登録者

Hofmeister, D.L.,Seltzner, C.A.,Bockhaus, N.J.,Thoden, J.B.,Holden, H.M. (登録日: 2022-08-23, 公開日: 2022-11-23, 最終更新日: 2023-10-25)

• 主引用文献: Hofmeister, D.L.,Seltzner, C.A.,Bockhaus, N.J.,Thoden, J.B.,Holden, H.M.; Investigation of the enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-d-glucuronic acid in Psychrobacter cryohalolentis K5 T.; Protein Sci., 32:e4502-e4502, 2023; PubMed: 36346293; DOI: 10.1002/pro.4502

実験手法

X-RAY DIFFRACTION (1 Å)