8E74

Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor

Summary for 8E74

Entry DOI	10.2210/pdb8e74/pdb
EMDB information	27935
Descriptor	Transcription termination/antitermination protein NusG, MAGNESIUM ION, DNA-directed RNA polymerase subunit alpha, ... (10 entities in total)
Functional Keywords	rna polymerase, transcription factor, elongation, pausing, transcription-transferase-dna complex, transcription-dna-rna complex, transcription/dna/rna
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	9
Total formula weight	435987.69
Authors	Delbeau, M.,Darst, S.A.,Campbell, E.A. (deposition date: 2022-08-23, release date: 2023-03-22, Last modification date: 2023-10-11)
Primary citation	Delbeau, M.,Omollo, E.O.,Froom, R.,Koh, S.,Mooney, R.A.,Lilic, M.,Brewer, J.J.,Rock, J.,Darst, S.A.,Campbell, E.A.,Landick, R. Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis. Mol.Cell, 83:1474-1488.e8, 2023 Cited by PubMed: 37116494 DOI: 10.1016/j.molcel.2023.04.007 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.94 Å)

Structure validation