8E72

Treponema lecithinolyticum beta-glucuronidase in complex with a ciprofloxacin-glucuronide conjugate

8E72 の概要

• エントリーDOI: 10.2210/pdb8e72/pdb
• 分子名称: Glycosyl hydrolase family 2, TIM barrel domain protein, 3-carboxy-1-cyclopropyl-6-fluoro-7-(4-beta-D-glucopyranuronosyl-3,4-dihydropyrazin-1(2H)-yl)-4-oxo-1,4-dihydroquinoline, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: glycoside hydrolase family 2, tim barrel domain, hydrolase
• 由来する生物種: Treponema lecithinolyticum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 145599.67

構造登録者

Lietzan, A.D.,Redinbo, M.R. (登録日: 2022-08-23, 公開日: 2023-06-21, 最終更新日: 2023-10-25)

• 主引用文献: Lietzan, A.D.,Simpson, J.B.,Walton, W.G.,Jariwala, P.B.,Xu, Y.,Boynton, M.H.,Liu, J.,Redinbo, M.R.; Microbial beta-glucuronidases drive human periodontal disease etiology.; Sci Adv, 9:eadg3390-eadg3390, 2023; PubMed: 37146137; DOI: 10.1126/sciadv.adg3390

実験手法

X-RAY DIFFRACTION (1.95 Å)