8E6U
Human TRPM2 ion channel in 1 mM F-dADPR
Summary for 8E6U
Entry DOI | 10.2210/pdb8e6u/pdb |
Related | 6mix |
EMDB information | 27926 |
Descriptor | Transient receptor potential cation channel subfamily M member 2, [(2R,3S,5R)-5-(6-amino-8-phenyl-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3S,4S,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name) (2 entities in total) |
Functional Keywords | trpm2, trp, adpr, adp-ribose, nudt9h, nudt9, calcium, ion channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 690620.05 |
Authors | |
Primary citation | Wang, L.,Fu, T.-M. A unified mechanism for human TRPM2 activation, desensitization and inhibition To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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