8E5Q

Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150303 Complex

8E5Q の概要

• エントリーDOI: 10.2210/pdb8e5q/pdb
• 分子名称: Sulfotransferase oxamniquine resistance protein, [2-(dihydroxyamino)-4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)phenyl]methanol, ADENOSINE-3'-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: sulfotransferase, parasite, drug resistance, transferase
• 由来する生物種: Schistosoma mansoni
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30944.34

構造登録者

Taylor, A.B.,Alwan, S.N. (登録日: 2022-08-22, 公開日: 2023-07-26, 最終更新日: 2024-05-22)

• 主引用文献: Alwan, S.N.,Taylor, A.B.,Rhodes, J.,Tidwell, M.,McHardy, S.F.,LoVerde, P.T.; Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.; Plos Pathog., 19:e1011018-e1011018, 2023; PubMed: 37428793; DOI: 10.1371/journal.ppat.1011018

実験手法

X-RAY DIFFRACTION (1.33 Å)