8E3E

ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10)

Summary for 8E3E

• Entry DOI: 10.2210/pdb8e3e/pdb
• Descriptor: Zinc finger and BTB domain-containing protein 7A, DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ... (5 entities in total)
• Functional Keywords: gene expression, dna binding protein-dna complex, dna binding protein, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 97008.92

Authors

Horton, J.R.,Ren, R.,Cheng, X. (deposition date: 2022-08-17, release date: 2023-02-08, Last modification date: 2023-10-25)

• Primary citation: Ren, R.,Horton, J.R.,Chen, Q.,Yang, J.,Liu, B.,Huang, Y.,Blumenthal, R.M.,Zhang, X.,Cheng, X.; Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.; J.Biol.Chem., 299:102885-102885, 2023; PubMed: 36626981; DOI: 10.1016/j.jbc.2023.102885

Experimental method

X-RAY DIFFRACTION (2.99 Å)