8E3E
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10)
Summary for 8E3E
Entry DOI | 10.2210/pdb8e3e/pdb |
Descriptor | Zinc finger and BTB domain-containing protein 7A, DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ... (5 entities in total) |
Functional Keywords | gene expression, dna binding protein-dna complex, dna binding protein, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 97008.92 |
Authors | Horton, J.R.,Ren, R.,Cheng, X. (deposition date: 2022-08-17, release date: 2023-02-08, Last modification date: 2023-10-25) |
Primary citation | Ren, R.,Horton, J.R.,Chen, Q.,Yang, J.,Liu, B.,Huang, Y.,Blumenthal, R.M.,Zhang, X.,Cheng, X. Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J.Biol.Chem., 299:102885-102885, 2023 Cited by PubMed: 36626981DOI: 10.1016/j.jbc.2023.102885 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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