8E32

E. coli 50S ribosome bound to compound streptogramin analogs SA1 and SB1

This is a non-PDB format compatible entry.

Summary for 8E32

• Entry DOI: 10.2210/pdb8e32/pdb
• EMDB information: 27852 27854 27855 27857 27858
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L34, (3R,4R,5E,10E,12E,14S,16R,23S,26aR)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-yn-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione, ... (13 entities in total)
• Functional Keywords: e. coli ribosome, streptogramin a, streptogramin b, antibiotics, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Escherichia coli; More
• Total number of polymer chains: 10
• Total formula weight: 1110501.38

Authors

Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2022-08-16, release date: 2023-06-28, Last modification date: 2024-06-12)

• Primary citation: Takahashi, Y.,Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B.; Potential for clicked streptogramin analogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.35 Å)