8E2U

HMPV F monomer bound to RSV-199 Fab

Summary for 8E2U

Entry DOI	10.2210/pdb8e2u/pdb
EMDB information	27846
Descriptor	Fusion glycoprotein F0, RSV-199 light chain, RSV-199 heavy chain (3 entities in total)
Functional Keywords	human antibodies, rsv and mpv fusion protein, complex cryo-em structure, viral protein and antiviral protein, biosynthetic protein
Biological source	Human metapneumovirus A (human) More
Total number of polymer chains	3
Total formula weight	94802.91
Authors	Wen, X.,Jardetzky, T.S. (deposition date: 2022-08-16, release date: 2023-08-16, Last modification date: 2023-08-23)
Primary citation	Wen, X.,Suryadevara, N.,Kose, N.,Liu, J.,Zhan, X.,Handal, L.S.,Williamson, L.E.,Trivette, A.,Carnahan, R.H.,Jardetzky, T.S.,Crowe Jr., J.E. Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode. Cell Host Microbe, 31:1288-1300.e6, 2023 Cited by PubMed: 37516111 DOI: 10.1016/j.chom.2023.07.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.48 Å)

Structure validation