8E21

The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034

Summary for 8E21

• Entry DOI: 10.2210/pdb8e21/pdb
• Descriptor: Polymerase acidic protein, MANGANESE (II) ION, 5-hydroxy-6-oxo-N-[2-(pyridin-4-yl)ethyl]-2-{[2-(trifluoromethyl)phenyl]methyl}-3,6-dihydropyrimidine-4-carboxamide, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein
• Biological source: Influenza A virus (A/Luxembourg/43/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 24441.52

Authors

Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W. (deposition date: 2022-08-12, release date: 2022-09-14, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W.; The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023034; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.61 Å)