8E0X
DAHP (3-deoxy-D-arabinoheptulosonate-7-phosphate) Synthase complexed with Mn(II), PEP, and Pi in unbound:(bound)2:other Conformations
Summary for 8E0X
Entry DOI | 10.2210/pdb8e0x/pdb |
Descriptor | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... (5 entities in total) |
Functional Keywords | dahp synthase inhibitor, dahp oxime complex, lyase |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 4 |
Total formula weight | 153493.14 |
Authors | Berti, P.J.,Junop, M.S.,Grainger, R. (deposition date: 2022-08-09, release date: 2022-10-12, Last modification date: 2023-10-18) |
Primary citation | Balachandran, N.,Grainger, R.A.,Rob, T.,Liuni, P.,Wilson, D.J.,Junop, M.S.,Berti, P.J. Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation. Biochemistry, 61:2229-2240, 2022 Cited by PubMed: 36197914DOI: 10.1021/acs.biochem.2c00465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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