8E0T

DAHP (3-deoxy-D-arabinoheptulosonate-7-phosphate) Synthase complexed with DAHP Oxime in unbound:(bound)2:other conformations

Summary for 8E0T

Entry DOI	10.2210/pdb8e0t/pdb
Descriptor	Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive, DAHP Oxime (3 entities in total)
Functional Keywords	dahp synthase inhibitor, dahp oxime complex, lyase
Biological source	Escherichia coli K-12
Total number of polymer chains	4
Total formula weight	153072.54
Authors	Berti, P.J.,Junop, M.S.,Grainger, R. (deposition date: 2022-08-09, release date: 2022-10-12, Last modification date: 2023-10-18)
Primary citation	Balachandran, N.,Grainger, R.A.,Rob, T.,Liuni, P.,Wilson, D.J.,Junop, M.S.,Berti, P.J. Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation. Biochemistry, 61:2229-2240, 2022 Cited by PubMed: 36197914 DOI: 10.1021/acs.biochem.2c00465 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation