8DZW

RSV F trimer bound to RSV-199 Fab

This is a non-PDB format compatible entry.

Summary for 8DZW

• Entry DOI: 10.2210/pdb8dzw/pdb
• EMDB information: 27808
• Descriptor: RSV fusion protein, RSV-199 Light chain protein, RSV-199 Heavy chain protein (3 entities in total)
• Functional Keywords: human antibodies, rsv and mpv fusion protein, complex cryo-em structure, viral protein and antiviral protein, structural protein
• Biological source: Human respiratory syncytial virus A2; More
• Total number of polymer chains: 9
• Total formula weight: 302315.70

Authors

Wen, X.,Jardetzky, T.S. (deposition date: 2022-08-08, release date: 2023-08-16, Last modification date: 2023-08-23)

• Primary citation: Wen, X.,Suryadevara, N.,Kose, N.,Liu, J.,Zhan, X.,Handal, L.S.,Williamson, L.E.,Trivette, A.,Carnahan, R.H.,Jardetzky, T.S.,Crowe Jr., J.E.; Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.; Cell Host Microbe, 31:1288-1300.e6, 2023; PubMed: 37516111; DOI: 10.1016/j.chom.2023.07.002

Experimental method

ELECTRON MICROSCOPY (2.46 Å)