8DZH

Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody MB.02

8DZH の概要

• エントリーDOI: 10.2210/pdb8dzh/pdb
• EMDBエントリー: 27798 27799 27800
• 分子名称: Spike glycoprotein, antibody MB.02 heavy chain, antibody MB.02 light chain, ... (5 entities in total)
• 機能のキーワード: viral protein, human antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 517386.71

構造登録者

Hu, Y.,Xiong, Y. (登録日: 2022-08-07, 公開日: 2022-08-31, 最終更新日: 2024-10-30)

• 主引用文献: Ren, P.,Hu, Y.,Peng, L.,Yang, L.,Suzuki, K.,Fang, Z.,Bai, M.,Zhou, L.,Feng, Y.,Zou, Y.,Xiong, Y.,Chen, S.; Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.; Signal Transduct Target Ther, 8:281-281, 2023; PubMed: 37518189; DOI: 10.1038/s41392-023-01509-1

実験手法

ELECTRON MICROSCOPY (3.2 Å)