8DXT

Fab arm of antibody GAR12 bound to the receptor binding domain of SARS-CoV-2.

8DXT の概要

• エントリーDOI: 10.2210/pdb8dxt/pdb
• 分子名称: Light chain of Fab arm of antibody GAR12, Heavy chain of Fab arm of antibody GAR12, Spike protein S1, ... (5 entities in total)
• 機能のキーワード: anti-cov-2, antibodies, convalescent patients, receptor binding domain., antiviral protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71664.88

構造登録者

Langley, D.B.,Christ, D.,Henry, J.Y. (登録日: 2022-08-03, 公開日: 2023-01-18, 最終更新日: 2023-10-25)

• 主引用文献: Rouet, R.,Henry, J.Y.,Johansen, M.D.,Sobti, M.,Balachandran, H.,Langley, D.B.,Walker, G.J.,Lenthall, H.,Jackson, J.,Ubiparipovic, S.,Mazigi, O.,Schofield, P.,Burnett, D.L.,Brown, S.H.J.,Martinello, M.,Hudson, B.,Gilroy, N.,Post, J.J.,Kelleher, A.,Jack, H.M.,Goodnow, C.C.,Turville, S.G.,Rawlinson, W.D.,Bull, R.A.,Stewart, A.G.,Hansbro, P.M.,Christ, D.; Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.; Nat Commun, 14:687-687, 2023; PubMed: 36755042; DOI: 10.1038/s41467-023-36295-5

実験手法

X-RAY DIFFRACTION (2.25 Å)