8DV6

Zika virus envelope protein structure in complex with a potent Human mAb

これはPDB形式変換不可エントリーです。

8DV6 の概要

• エントリーDOI: 10.2210/pdb8dv6/pdb
• 分子名称: Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain (3 entities in total)
• 機能のキーワード: zika virus, envelope protein, neutralizing antibody, neutralization mechanism, flavivirus, viral protein, viral protein-immune system complex
• 由来する生物種: Zika virus ZIKV/Human/Cambodia/FSS13025/2010 (ZIKV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 188458.73

構造登録者

Cameron, A.,Puhl, A.C.,deSilva, A.M.,Premkumar, L. (登録日: 2022-07-28, 公開日: 2023-01-04, 最終更新日: 2023-10-25)

• 主引用文献: Adams, C.,Carbaugh, D.L.,Shu, B.,Ng, T.S.,Castillo, I.N.,Bhowmik, R.,Segovia-Chumbez, B.,Puhl, A.C.,Graham, S.,Diehl, S.A.,Lazear, H.M.,Lok, S.M.,de Silva, A.M.,Premkumar, L.; Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.; Plos Pathog., 19:e1010814-e1010814, 2023; PubMed: 36626401; DOI: 10.1371/journal.ppat.1010814

実験手法

X-RAY DIFFRACTION (3.38 Å)