8DTK

Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace

8DTK の概要

• エントリーDOI: 10.2210/pdb8dtk/pdb
• EMDBエントリー: 27703
• 分子名称: Spike protein S1, DH1047 Fab Light Chain, DH1047 Fab Heavy Chain, ... (4 entities in total)
• 機能のキーワード: rbd, fab, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50454.03

構造登録者

May, A.J.,Manne, K.,Acharya, P. (登録日: 2022-07-25, 公開日: 2023-08-02, 最終更新日: 2024-02-28)

• 主引用文献: Malewana, R.D.,Stalls, V.,May, A.,Lu, X.,Martinez, D.R.,Schafer, A.,Li, D.,Barr, M.,Sutherland, L.L.,Lee, E.,Parks, R.,Beck, W.E.,Newman, A.,Bock, K.W.,Minai, M.,Nagata, B.M.,DeMarco, C.T.,Denny, T.N.,Oguin 3rd, T.H.,Rountree, W.,Wang, Y.,Mansouri, K.,Edwards, R.J.,Sempowski, G.D.,Eaton, A.,Muramatsu, H.,Henderson, R.,Tam, Y.,Barbosa, C.,Tang, J.,Cain, D.W.,Santra, S.,Moore, I.N.,Andersen, H.,Lewis, M.G.,Golding, H.,Seder, R.,Khurana, S.,Montefiori, D.C.,Pardi, N.,Weissman, D.,Baric, R.S.,Acharya, P.,Haynes, B.F.,Saunders, K.O.; Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.; Biorxiv, 2023; PubMed: 38187726; DOI: 10.1101/2023.12.18.572191

実験手法

ELECTRON MICROSCOPY (3.77 Å)