8DTD

Crystal Structure of FosB from Bacillus cereus with Zinc and Phosphonoformate

Summary for 8DTD

Entry DOI	10.2210/pdb8dtd/pdb
Descriptor	Metallothiol transferase FosB, PHOSPHONOFORMIC ACID, ZINC ION, ... (4 entities in total)
Functional Keywords	fosfomycin, antibiotic resistance, thiol-transferase, antibiotic, dimer, transferase-antibiotic complex, transferase
Biological source	Bacillus cereus ATCC 10987
Total number of polymer chains	2
Total formula weight	33359.80
Authors	Travis, S.,Gilbert, N.C.,Thompson, M.K. (deposition date: 2022-07-25, release date: 2023-08-02, Last modification date: 2024-08-14)
Primary citation	Travis, S.,Green, K.D.,Gilbert, N.C.,Tsodikov, O.V.,Garneau-Tsodikova, S.,Thompson, M.K. Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate. Biochemistry, 62:109-117, 2023 Cited by PubMed: 36525630 DOI: 10.1021/acs.biochem.2c00566 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation