8DRX

Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2)

Summary for 8DRX

Entry DOI	10.2210/pdb8drx/pdb
Descriptor	Fusion protein of 3C-like proteinase nsp5 and nsp10-nsp11 (C10) cut site, SODIUM ION (3 entities in total)
Functional Keywords	viral protease, sars-cov-2, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More
Total number of polymer chains	2
Total formula weight	67882.44
Authors	Lee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Paetzel, M.,Strynadka, N.C.J. (deposition date: 2022-07-21, release date: 2022-09-21, Last modification date: 2023-10-18)
Primary citation	Lee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Gentile, F.,Ton, A.T.,Ng, M.,Cherkasov, A.,Strynadka, N.C.J.,Paetzel, M. X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13:5196-5196, 2022 Cited by PubMed: 36057636 DOI: 10.1038/s41467-022-32854-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation